丽莎·兰伯特博士.D.
家乡:肯塔基州米切尔堡
1985年加入查塔姆国际事务研究所
兴趣的学术领域
Molecular evolution of iron transport proteins (especially, 转铁蛋白, DMT1, hemojuvelin; iron uptake in bacteria, especially ferric binding proteins; co-evolution of proteins
个人兴趣领域
Bridge, computer games, reading (science fiction and mysteries), travel
传记
1980年获得生物学学士学位后, 毕业于弗曼大学(皮毛man University), I studied Genetics at Indiana University-Bloomington (PhD 1985). 就在我交论文的两天之后, I drove to Pittsburgh to join the faculty at Chatham, where I have also served as department chair (生物学), 分部主席(自然科学), 副院长(学术事务), 项目主任(生物学硕士). 在2013日历年, I did a sabbatical at the Harvard University School of Public 健康, Department of Genetics and Complex Diseases. My research focuses on the evolution of the genes involved in iron transport and regulation using primarily a 生物信息学 approach (phylogenetics, 蛋白质建模, 等.) I have served as a panel reviewer for the NSF and NIH, as an external reviewer for several colleges, and as an ad hoc reviewer for a number of journals including BMC Genomics and the Journal of Molecular Evolution. Over the years I've offered over 20 different courses including genetics, 生物统计学, 生物信息学, 研究方法, 以及发育生物学. I've also had the pleasure of supervising 12 thesis students and over 65 undergraduate tutorial students. 我嫁给了博士. Michael Lambert of the Pittsburgh Supercomputing Center, and we have two children and two cats.
教育
- B.S. 生物学, 皮毛man University (Greenville, SC), 1980 (magna cum laude)
- Ph.D., Indiana University (Bloomington, IN), 1985
奖
- NSF S-STEM Award DUE-1259577 ""Preparing Female Scholars for Careers in 生物学, 化学与生物化学," $625,701
- NIH F33 Fellowship-National 研究 Service 奖 for Senior Fellows (2013 sabbatical at Harvard)
- Project Bedrock Digital Scholar Mentor (HHMI-funded BioQuest initiative) 2002
- NSF CCLI grant (co-PI) - The Fluorescence Spectrometer in the 本科 化学istry and 生物学 Curriculum (1999)
- 1989 EDPRESS Award National Winner, best “How To Do It” article
- Project Kaleidoscope, 教师 for the 21st Century, Class of 1995
- NSF Supplementary Grant for Small College Investigators (1990)
- Phi Beta Kappa(1980年)
- Rhodes Scholarship District Finalist (1979)
组织
- 美国遗传学会
- Phi Beta Kappa
- 美国微生物学会
认证
- NIH Responsible Conduct of 研究 Certificate (spring 2013)
选定的出版物
- Molecular characterization of a homolog of the ferric-uptake regulator, 皮毛, from the marine bacterium Marinobacter algicola DG893. (2015)生物金属28(1):197-206. Barker RA, Tisnado J, Lambert LA, Gärdes A, Carrano MW, Carrano PN, Gillian C, Carrano CJ.
- Bordetella pertussis FbpA binds both unchelated iron and iron-siderophore complexes (2014) Biochemistry 53 (24): 3952–3960. 巴纳吉, S; Weerasinghe, AJ; Parker-Siburt, CJ; Kreulen, RT; Armstrong, SK; Brickman, TJ; 兰伯特拉; Crumbliss, AL
- Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: A role for boron in iron transport in marine life (2013) J. Am. 化学. Soc. 135 (39):14504–14507. Weerasighe, AJ; Amin, SA; Barker, R; Othman, T; Romano, AN; Siburt, CJP; Tisnado, J; 兰伯特拉; Huxford, T; Carrano, CJ; Crumbliss, AL
- Molecular evolution of the 转铁蛋白 family and associated receptors. Biochim. BioPhys. 学报. (2012) 1820:244-255. 兰伯特拉.
- Evidence of Fe3+ interaction with the plug domain of the outer membrane 转铁蛋白 receptor protein of Neisseria gonorrhoeae: Implications for Fe transport. (2012) Metallomics:361-372 巴纳吉, S; Siburt, CJP; Mistry, S; Noto, JM; DeArmond, P; Fitzgerald, MC; 兰伯特拉; Cornelissen, CN; Crumbliss, AL
- Molecular evolution and selection pressure in alpha-class carbonic anhydrase family members. Biochim. BioPhys. 学报. (2011) 1814(12):1854–1861. McDevitt ME; Lambert LA.
- The structure and evolution of the murine inhibitor of carbonic anhydrase: A member of the 转铁蛋白 superfamily. (2010)蛋白质科学，19(9):1616-1626. Eckenroth BE, Mason AB, McDevitt ME, Lambert LA, Everse SJ.
- Molecular evolution and characterization of hepcidin gene products in vertebrates. (2008)基因:415(1-2):40-48. Hilton KM; Lambert LA
- A novel murine protein with no effect on iron homeostasis is homologous to 转铁蛋白 and is the putative inhibitor of carbonic anhydrase (2007) Biochemical Journal 406(1): 85-95. Wang F, Lothrop AP, James NG, Griffiths TA, Lambert LA, et al.
- Molecular evolution of hemojuvelin and the repulsive guidance molecule (RGM) family. (2007) Journal of Molecular Evolution Jul;65(1):68-81. Camus, LM; 兰伯特拉.
- Molecular evolution of the 转铁蛋白 receptor/glutamate carboxypeptidase II family. (2007) Journal of Molecular Evolution 64(1):113-28. 兰伯特拉; Mitchell, SL.
- Evolution of the 转铁蛋白 family: Conservation of residues associated with iron and anion binding. (2005) Comparative Biochemistry and Physiology, Part B 142(2):129-41. Lambert, L; Perri, H; Halbrooks, PJ; Mason, AB.
- Evolution of duplications in the 转铁蛋白 family of proteins. (2005) Comparative Biochemistry and Physiology, Part B.140(1):11-25. 兰伯特拉; Perri, H; Meehan, T.
- Disease Detective: A game simulation of a food poisoning investigation. (1989) American 生物学 Teacher 51(7): 429-432. (EDPRESS奖得主)兰伯特，洛杉矶.
选定的演讲
- Babacanec C, Lambert LA. 2008. “Bioinformatics Approach to the Identification of Potential Sites of Interaction between HFE and TFR2.” Poster presentation: Symposium on Metals in Biological Systems, 杜肯大学 , 2008年12月.
- 威廉姆斯，KR，兰伯特洛杉矶. 2007. “Evolutionary Conservation of Parvovirus VP2 and Transferrin Receptor 1 Residues.” Poster presentation: ABASM Regional Conference, November 2007.
- Haslego-Hilton K, Lambert LA. 2006. “Evolution of hepcidin: an antimicrobial peptide.” Poster presentation: ABASM Regional Conference, November 2006.
- Perri H, Johnson M, Lambert LA. 2004. “Patterns of amino acid conservation in clostridial neurotoxins.” Poster presentation: ABASM Regional Conference, November 2004.